Inhibition of Prostaglandin Synthetase in Brain explains the Anti-pyretic Activity of Paracetamol (4-Acetamidophenol)

Inhibition of Prostaglandin Synthesis as a Mechanism of Action for Aspirin-like Drugs

John R. Vane · Nature New Biology · 1971 · 8.6K citations

Life Sciences, Medicinal Chemistry, Pharmacology +10

The Pharmacological Basis of Therapeutics

American Journal of Health-System Pharmacy · 1976 · 8.2K citations

Medicine, Pharmacology, Pharmacotherapy +10

Aspirin Selectively Inhibits Prostaglandin Production in Human Platelets

J. Bryan Smith, A.L. Willis · Nature New Biology · 1971 · 1.5K citations

Medicine, Pharmacology, Pharmacotherapy +14

Indomethacin and Aspirin abolish Prostaglandin Release from the Spleen

S. H. Ferreira, Salvador Moncada, John R. Vane · Nature New Biology · 1971 · 934 citations

Veterinary Medicine, Pharmacology, Inflammation +5

The Pharmacological Basis of Therapeutics.

Annals of Internal Medicine · 1971 · 885 citations

Medicine, Pharmacology, Pharmacotherapy +8