Higher Hematocrit Improves Liver Blood Flow and Metabolism During Cardiopulmonary Bypass in Piglets

Abstract

Hemodilution results in a tendency towards reduced liver blood flow during CPB; much worse is the resulting impaired liver metabolism, independent of reduced blood flow and pressure. Avoidance of low hematocrit during CPB may be a useful adjunct to preserve liver function in patients undergoing cardiac surgery with long duration CPB and DHCA.