Effects of the Prostaglandins on Hormone-induced Mobilization of Free Fatty Acids *

Abstract

About 30 years ago, Goldblatt (1, 2) and von Euler (3, 4) showed that human and ovine seminal plasma contain an acidic lipid (prostaglandin) with vasodepressor activity and smooth muscle-stimu- lating activity. The early studies have been sum- marized by von Euler (5, 6). In 1960 Berg- strom and Sjdvall isolated from sheep vesicular glands a highly potent crystalline material, prostaglandin E1 (PGE1) Further studies showed that