Running exercise increases tumor necrosis factor-α secreting from mesenteric fat in insulin-resistant rats

Adipose Expression of Tumor Necrosis Factor-α: Direct Role in Obesity-Linked Insulin Resistance

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Medicine, Endocrinology, Molecular Biology +17

THE GLUCOSE FATTY-ACID CYCLE ITS ROLE IN INSULIN SENSITIVITY AND THE METABOLIC DISTURBANCES OF DIABETES MELLITUS

P J Randle, P. B. Garland, C. N. Hales et al. · The Lancet · 1963 · 5.2K citations

Life Sciences, Endocrinology, Physiology +10

IRS-1-Mediated Inhibition of Insulin Receptor Tyrosine Kinase Activity in TNF-α- and Obesity-Induced Insulin Resistance

Gökhan S. Hotamışlıgil, Pascal Peraldi, Adriane I. Budavari et al. · Science · 1996 · 2.6K citations

Life Sciences, Endocrinology, Molecular Biology +17

Mechanism of free fatty acid-induced insulin resistance in humans.

Michael Roden, Thomas B. Price, Gianluca Perseghin et al. · Journal of Clinical Investigation · 1996 · 1.5K citations · Full text

Life Sciences, Endocrinology, Physiology +17

The expression of tumor necrosis factor in human adipose tissue. Regulation by obesity, weight loss, and relationship to lipoprotein lipase.

Philip A. Kern, Mehrnoosh Saghizadeh, Juling Ong et al. · Journal of Clinical Investigation · 1995 · 1.3K citations · Full text

Life Sciences, Molecular Biology, Physiology +10