RELEASE OF PROSTACYCLIN IN VIVO AND ITS ROLE IN MAN

Arterial walls generate from prostaglandin endoperoxides a substance (prostaglandin X) which relaxes strips of mesenteric and coeliac arteries and inhibits platelet aggregation

Stuart Bunting, Salvador Moncada, John R. Vane et al. · Prostaglandins · 1976 · 955 citations

Medicine, Physiology, Signal Transduction +11

ARTERIAL THROMBOSIS, INTRAUTERINE DEATH AND "LUPUS" ANTICOAGULANT: DETECTION OF IMMUNOGLOBULIN INTERFERING WITH PROSTACYCLIN FORMATION

L Carreras, S.J. Machin, R DEMAN et al. · The Lancet · 1981 · 554 citations

Medicine, Obstetrics, Pathology +16

Prostacyclin is a circulating hormone

Salvador Moncada, Ryszard Korbut, Stuart Bunting et al. · Nature · 1978 · 379 citations

Life Sciences, Endocrinology, Hormone Biochemistry +2

Generation of prostacyclin by lungs in vivo and its release into the arterial circulation

Ryszard J. Gryglewski, Ryszard Korbut, A. Ocetkiewicz · Nature · 1978 · 374 citations

Medicine, Pharmacology, Pharmacodynamics +5

Prostacyclin is not a circulating hormone in man

Ian A. Blair, Susan E. Barrow, Keith Waddell et al. · Prostaglandins · 1982 · 286 citations

Life Sciences, Biochemistry, Endocrinology +3