Concepedia

Combined Transfection of the Three Transcriptional Factors, PDX-1, NeuroD1, and MafA, Causes Differentiation of Bone Marrow Mesenchymal Stem Cells into Insulin-Producing Cells

Guo Qing-Song, Zhu Mingyan, Lei Wang, Xiangjun Fan, Yuhua Lu, Zhiwei Wang, Zhu Sha-Jun, Wang Yao, Yan Huang

Experimental Diabetes Research · 2012 · 51 citations · 21 references

DOIFull text

Open access

Abstract

These findings suggest major implications for cell replacement strategies in generation of surrogate β-cells for the treatment of diabetes.

References

21

Initiation of Mammalian Liver Development from Endoderm by Fibroblast Growth Factors

Joonil Jung, Ming‐Hua Zheng, Mitchell Goldfarb et al. · Science · 1999 · 721 citations

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Direct Reprogramming of Adult Human Fibroblasts to Functional Neurons under Defined Conditions

Rajesh Ambasudhan, Maria Talantova, R.L. Coleman et al. · Cell stem cell · 2011 · 484 citations · Full text

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Clonal identification and characterization of self-renewing pluripotent stem cells in the developing liver

Atsushi Suzuki, Yun‐Wen Zheng, Shin Kaneko et al. · The Journal of Cell Biology · 2002 · 353 citations · Full text

Stem-cell research

Diane Gershon · Nature · 2003 · 351 citations

Generation of Insulin-Producing Cells from Human Bone Marrow Mesenchymal Stem Cells by Genetic Manipulation

Ohad Karnieli, Yael Izhar-Prato, Shlomo Bulvik et al. · Stem Cells · 2007 · 288 citations · Full text