Histone deacetylases inhibitor Trichostatin A ameliorates DNFB-induced allergic contact dermatitis and reduces epidermal Langerhans cells in mice

Structures of a histone deacetylase homologue bound to the TSA and SAHA inhibitors

Michael S. Finnin, Jill R. Donigian, Alona Cohen et al. · Nature · 1999 · 1.7K citations

Histone Modifications, Chromatin, Chromatin Structure +11

Genome-wide Mapping of HATs and HDACs Reveals Distinct Functions in Active and Inactive Genes

Zhibin Wang, Chongzhi Zang, Kairong Cui et al. · Cell · 2009 · 1.3K citations · Full text

Natural Sciences, Genetics, Genome Structure +11

Langerin, a Novel C-Type Lectin Specific to Langerhans Cells, Is an Endocytic Receptor that Induces the Formation of Birbeck Granules

Jenny Valladeau, Odile Ravel, Colette Dezutter‐Dambuyant et al. · Immunity · 2000 · 938 citations

Signal Transduction, Cell Signaling, Cell Trafficking +9

Deacetylase inhibition promotes the generation and function of regulatory T cells

Ran Tao, Edwin F. de Zoeten, Engin Özkaynak et al. · Nature Medicine · 2007 · 898 citations

Signal Transduction, Cell Regulation, T-regulatory Cell +9

Epidermal Langerhans Cell-Deficient Mice Develop Enhanced Contact Hypersensitivity

Daniel H. Kaplan, Mathew C. Jenison, Sem Saeland et al. · Immunity · 2005 · 546 citations · Full text

Autoimmune Disease, Immunology, Skin Allergy +5