Concepedia

The skewing to Th1 induced by lentinan is directed through the distinctive cytokine production by macrophages with elevated intracellular glutathione content

Yukie Murata, T Shimamura, Tomoyuki Tagami, Fumihiko Takatsuki, Junji Hamuro

International Immunopharmacology · 2002 · 113 citations · 54 references

DOI

Concepts

References

54

M-1/M-2 Macrophages and the Th1/Th2 Paradigm

Charles D. Mills, Kristi Kincaid, Jennifer Alt et al. · The Journal of Immunology · 2000 · 3.2K citations

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Interleukin 4 potently enhances murine macrophage mannose receptor activity: a marker of alternative immunologic macrophage activation.

Michael Stein, Satish Keshav, Nicholas Harris et al. · The Journal of Experimental Medicine · 1992 · 1.9K citations · Full text

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Interleukin 10 (IL-10) inhibits human lymphocyte interferon gamma-production by suppressing natural killer cell stimulatory factor/IL-12 synthesis in accessory cells.

Annalisa D’Andrea, Miguel Aste-Amézaga, Nicholas M. Valiante et al. · The Journal of Experimental Medicine · 1993 · 1.4K citations · Full text

, , +12

The Toll-like receptor 2 is recruited to macrophage phagosomes and discriminates between pathogens

David M. Underhill, Adrian Ozinsky, Adeline M. Hajjar et al. · Nature · 1999 · 1.4K citations

, , +12

Interleukin-12: a cytokine produced by antigen-presenting cells with immunoregulatory functions in the generation of T-helper cells type 1 and cytotoxic lymphocytes

Giorgio Trinchieri · Blood · 1994 · 1.1K citations · Full text

, , +17