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Therapeutic effects of pindolol on behavioral disturbances associated with organic brain disease: A double-blind study
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1987
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NeuropsychologyPsychotropic MedicationPsychopharmacologyTherapeutic EffectsNeuropsychiatryBrain DiseasePharmacotherapyPindolol TreatmentImpulsivitySocial SciencesNeurologyNeuropathologyPsychoactive DrugPsychiatryBehavioral NeuroscienceBehavioral DisturbancesOrganic Brain DiseaseNeuropharmacologyRehabilitationPlacebo-controlled Crossover StudyNeurophysiologyAddictionNeuroscienceBiological PsychiatryAnesthesiaMedicinePsychopathologyAnesthesiology
A double-blind, placebo-controlled crossover study was conducted to examine the effects of pindolol for the treatment of 11 patients with impulsive, explosive behaviors and other emotional-behavioral abnormalities as a consequence of brain disease or injury. Pindolol treatment was associated with significant therapeutic benefits without sedation and without the use-limiting side effects that occur with propranolol.