<i>In vivo</i> IL‐10 and TGF‐β production by PBMC from long‐term kidney transplant recipients with excellent graft function: a possible feedback mechanism participating in immunological stability

Abstract

The higher IL-10 production observed in long-term kidney transplant recipients supports the notion that this cytokine contributes in decreasing allogenic immune responses and allows prolongation of allograft survival. The balance between TGF-beta and IL-10 may be of paramount importance in graft acceptance.