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Clopidogrel Pharmacokinetics and Pharmacodynamics Vary Widely Despite Exclusion or Control of Polymorphisms (CYP2C19, ABCB1, PON1), Noncompliance, Diet, Smoking, Co-Medications (Including Proton Pump Inhibitors), and Pre-Existent Variability in Platelet Function

ThrombopoiesisThrombosisCardiovascular DiseasePharmacodynamics Vary WidelyBlood PlateletPharmacologyGenetic EpidemiologyHematologyProton Pump InhibitorsPharmacotherapyPharmacogenomicsClopidogrel PharmacokineticsPublic HealthPlatelet AntagonistMedicineAnticoagulantAtherosclerosis