Exacerbation of poststroke dementia by type 2 diabetes is associated with synergistic increases of β-secretase activation and β-amyloid generation in rat brains

Reversible middle cerebral artery occlusion without craniectomy in rats.

Enrique Zea Longa, Philip R. Weinstein, Shaun W. Carlson et al. · Stroke · 1989 · 7.5K citations · Full text

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Developments of a water-maze procedure for studying spatial learning in the rat

Richard Morris · Journal of Neuroscience Methods · 1984 · 7.2K citations

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β-Secretase Cleavage of Alzheimer's Amyloid Precursor Protein by the Transmembrane Aspartic Protease BACE

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Diabetes mellitus and the risk of dementia

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Medicine, Geriatric Medicine, Neurology +17

Combination of high-fat diet-fed and low-dose streptozotocin-treated rat: A model for type 2 diabetes and pharmacological screening

K. K. Srinivasan, Bhoomi Viswanad, Lydia Asrat et al. · Pharmacological Research · 2005 · 1.9K citations

Medicine, Endocrinology, Pharmacology +10