Prevention of Age-Related Macular Degeneration–Like Retinopathy by Rapamycin in Rats

Rapamycin fed late in life extends lifespan in genetically heterogeneous mice

Randy Strong, Z. Dave Sharp, James F. Nelson et al. · Nature · 2009 · 3.7K citations · Full text

Education, Genetics, Nutrition +15

mTOR regulates memory CD8 T-cell differentiation

Koichi Araki, Alexandra P. Turner, Virginia Shaffer et al. · Nature · 2009 · 1.6K citations · Full text

Life Sciences, Immunology, Molecular Biology +12

Regulation of Lifespan in Drosophila by Modulation of Genes in the TOR Signaling Pathway

Pankaj Kapahi, Brian M. Zid, Tony Harper et al. · Current Biology · 2004 · 1.3K citations · Full text

Education, Genetics, Molecular Biology +12

Suppression of retinal neovascularization in vivo by inhibition of vascular endothelial growth factor (VEGF) using soluble VEGF-receptor chimeric proteins.

Lloyd Paul Aiello, Eric A. Pierce, E D Foley et al. · Proceedings of the National Academy of Sciences · 1995 · 1.3K citations · Full text

Medicine, Ophthalmology, Vision Science +16

Influence of TOR kinase on lifespan in C. elegans

Tibor Vellai, Krisztina Takács‐Vellai, Yue Zhang et al. · Nature · 2003 · 1.1K citations

Life Sciences, Biology, Molecular Biology +13