Journal of Natural Products · 2007 · 74 citations · 13 references
PharmacyBotanyPlant SciencesDrug DiscoveryPlant BiochemistryStructure-activity RelationshipsMedicinal PlantsStructure-activity Relationship AnalysisTerpenoid BiosynthesisAbsolute Configuration AssignmentAbsolute Configuration DeterminationSesquiterpene Biosynthesis
Three new dimeric sesquiterpenoids, chloramultilides B-D ( 1- 3), along with 10 known sesquiterpenoids, were isolated from the whole plant of Chloranthus spicatus. Their structures were established by physical data (1D and 2D NMR, MS). The structure and absolute configuration of 1 was confirmed by X-ray crystallography. Compound 1 exhibited moderate in vitro antifungal activity.
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Shizukaol a, a sesquiterpene dimer from Chloranthus japonicus
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