Enamel Matrix Derivative Promotes Superoxide Production and Chemotaxis but Reduces Matrix Metalloproteinase‐8 Expression by Polymorphonuclear Leukocytes

Abstract

EMD has specific, differential actions on PMNs that suggest potential for enhancement of wound healing, bacterial and tissue debris clearance (O(2)(-) generation and chemotaxis), and suppression of tissue damage and degradation (MMP-8 ). Together, the data suggest that EMD enhances wound healing and reduces inflammation.