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Oxymorphone Active Uptake at the Blood–Brain Barrier and Population Modeling of its Pharmacokinetic–Pharmacodynamic Relationship

Pharmacokinetic ModelingBlood–brain BarrierMedicinePhysiologyPopulation ModelingNeuropharmacologyActive UptakePharmacotherapyDrug AbsorptionPharmacologyPhysiologically-based Pharmacokinetic ModelingPharmacokineticsPharmacodynamic Modeling