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Identification of a novel mutation in the dihydropyrimidine dehydrogenase gene in a patient with a lethal outcome following 5-fluorouracil administration and the determination of its frequency in a population of 500 patients with colorectal carcinoma

MedicineGeneticsDihydropyrimidine Dehydrogenase GeneColorectal CancerPathologyLethal OutcomeCancer GeneticsOncology5-Fluorouracil AdministrationCancer Research