Chemical Communications · 2012 · 15 citations · 22 references
Life SciencesBiochemistryChemistryBioorthogonal ChemistryCarbohydrate ChemistryGlycobiologyCarbohydrate ProtectionCarbohydrate SynthesisGlycan BiosynthesisGlycan StructureGlycosidic Bond FormationMonosaccharide ChemistryBranching Oligosaccharide SynthesisGlycan Building Block SynthesisGlycosylation Method DevelopmentGlycosylation Reagent DevelopmentMonosaccharide SynthesisOligomannose GlycosylationOligosaccharide Synthesis
We developed a facile synthesis to yield orthogonally protected mannose building blocks with high overall yields. The protection/glycosylation steps can be carried out in a successive manner without purification of intermediate products. This developed synthesis led to formation of linear/branched tri-, penta- and heptasaccharides.
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Gamma-Ray Flares from the Crab Nebula
A. A. Abdo, M. Ackermann, M. Ajello et al. · Science · 2011 · 362 citations · Full text
Natural Sciences, Astronomy, Physics +13