The Lancet · 1983 · 133 citations · 21 references
MedicinePharmacologyPharmacotherapyGastroenterologyGastrointestinal PharmacotherapyPain MedicineConstipation PharmacotherapyFunctional Gastrointestinal DisordersIrritable Bowel SyndromeOpioid AnalgesicsOpioid PharmacologyOpioid TherapyChronic Constipation PharmacotherapyChronic Constipation TreatmentChronic Idiopathic Constipation TreatmentConstipation PathophysiologyOpioid Antagonist Therapy
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Identification of two related pentapeptides from the brain with potent opiate agonist activity
Joel W. Hughes, Terry Smith, H. W. Kosterlitz et al. · Nature · 1975 · 3.8K citations
Opiate Receptor: Demonstration in Nervous Tissue
Candace B. Pert, Solomon H. Snyder · Science · 1973 · 2.4K citations
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Dynorphin Is a Specific Endogenous Ligand of the κ Opioid Receptor
Charles Chavkin, Iain F. James, Avram Goldstein · Science · 1982 · 1.2K citations