Concepedia

In vivo post-transcriptional gene silencing of α-1 antitrypsin by adeno-associated virus vectors expressing siRNA

Pedro E. Cruz, Christian Mueller, Travis Cossette, Alexandra Golant, Qiushi Tang, Stuart G. Beattie, Mark Brantly, Martha Campbell‐Thompson, Keith Blomenkamp, Jeffrey Teckman,

Laboratory Investigation · 2007 · 61 citations · 35 references

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35

Duplexes of 21-nucleotide RNAs mediate RNA interference in cultured mammalian cells

Sayda M. Elbashir, Jens Harborth, Winfried Lendeckel et al. · Nature · 2001 · 9.3K citations

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RNA interference is mediated by 21- and 22-nucleotide RNAs

Sayda M. Elbashir, Winfried Lendeckel, Thomas Tuschl · Genes & Development · 2001 · 3.3K citations · Full text

Fatality in mice due to oversaturation of cellular microRNA/short hairpin RNA pathways

Dirk Grimm, Konrad L. Streetz, Catherine L. Jopling et al. · Nature · 2006 · 1.7K citations

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Novel adeno-associated viruses from rhesus monkeys as vectors for human gene therapy

Guangping Gao, Mauricio R. Alvira, Lili Wang et al. · Proceedings of the National Academy of Sciences · 2002 · 1.5K citations · Full text

Functional anatomy of siRNAs for mediating efficient RNAi in Drosophila melanogaster embryo lysate

Sayda M. Elbashir · The EMBO Journal · 2001 · 1.4K citations · Full text

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