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Self-Assembly of a Tetrahedral Lectin into Predesigned Diamondlike Protein Crystals
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1999
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Crystal StructureProtein AssemblyBiomolecular Structure PredictionStructural BioinformaticsMolecular Self-assemblyMolecular BiologyProtein FoldingProtein X-ray CrystallographyCrystal FormationBiophysicsBiochemistryTetrahedral LectinCrystallographyStructural BiologyConcanavalin ANatural SciencesSelf-assemblyMedicineCarbohydrate-protein Interaction
Binding sites analogous to those of sp(3) carbon are presented by concanavalin A. This lectin has now been cross-linked with a bismannopyranoside which contains the C(2) spacer required to form the computer-modeled diamondlike three-dimensional protein lattice shown in the picture.