The character of inhibition of the metabolism of 1,2-benzopyrone (coumarin) by grapefruit juice in human

Grapefruit juice increases felodipine oral availability in humans by decreasing intestinal CYP3A protein expression.

Kenneth S. Lown, David G. Bailey, Robert J. Fontana et al. · Journal of Clinical Investigation · 1997 · 628 citations · Full text

Pharmacy, Pharmacokinetics, Pharmacology +11

Disposition of intravenous and oral cyclosporine after administration with grapefruit juice*

Murray P. Ducharme, L H Warbasse, David J. Edwards · Clinical Pharmacology & Therapeutics · 1995 · 351 citations

Pharmacy, Clinical Pharmacokinetics, Pharmacology +15

Inhibitory effect of grapefruit juice and its bitter principal, naringenin, on CYP1A2 dependent metabolism of caffeine in man.

Uwe Fuhr, K Klittich, A. H. Staib · British Journal of Clinical Pharmacology · 1993 · 243 citations · Full text

Medicine, Pharmacokinetics, Pharmacology +14

Grapefruit juice–felodipine interaction: Mechanism, predictability, and effect of naringin

David G. Bailey, J. Malcolm O. Arnold, Claudio Munoz et al. · Clinical Pharmacology & Therapeutics · 1993 · 229 citations

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Identification of 6',7'-dihydroxybergamottin, a cytochrome P450 inhibitor, in grapefruit juice.

David J. Edwards, Frank H. Bellevue, Patrick M. Woster · Drug Metabolism and Disposition · 1996 · 219 citations

Medicine, Biochemistry, Pharmacology +11