Hydrogen peroxide mediates reperfusion injury in the isolated rat heart

Canine myocardial reperfusion injury. Its reduction by the combined administration of superoxide dismutase and catalase.

S. Jolly, William J. Kane, Marc B. Bailie et al. · Circulation Research · 1984 · 907 citations · Full text

Medicine, Cardiology, Hemodynamic Management +12

Xanthine oxidase as a source of free radical damage in myocardial ischemia

David Chambers, D. H. Parks, G. C. Patterson et al. · Journal of Molecular and Cellular Cardiology · 1985 · 674 citations

Life Sciences, Biochemistry, Cardiology +15

Xanthine oxidase-derived hydrogen peroxide contributes to ischemia reperfusion-induced edema in gerbil brains.

Antonia Patt, Alden H. Harken, Lisa K. Burton et al. · Journal of Clinical Investigation · 1988 · 209 citations · Full text

Life Sciences, Neurobiology, Neuroscience +15

Involvement of hydrogen peroxide and hydroxyl radical in the ‘oxygen paradox’: Reduction of creatine kinase release by catalase, allopurinol or deferoxamine, but not by superoxide dismutase**

Charles E. Myers, Steven J. Weiss, M. M. Kirsh et al. · Journal of Molecular and Cellular Cardiology · 1985 · 168 citations

Life Sciences, Biochemistry, Physiology +16

Xanthine oxidase produces hydrogen peroxide which contributes to reperfusion injury of ischemic, isolated, perfused rat hearts.

Janet M. Brown, Lance S. Terada, Michael Grosso et al. · Journal of Clinical Investigation · 1988 · 140 citations · Full text

Life Sciences, Biochemistry, Physiology +14