Concepedia

Novel molecules that interact with microtubules and have functional activity similar to Taxol™

Lifeng He, George A. Orr, Susan Band Horwitz

Drug Discovery Today · 2001 · 144 citations · 74 references

DOI

Concepts

References

74

Plant antitumor agents. VI. Isolation and structure of taxol, a novel antileukemic and antitumor agent from Taxus brevifolia

M. C. Wani, Harold L. Taylor, Monroe E. Wall et al. · Journal of the American Chemical Society · 1971 · 4.1K citations

, , +10

Promotion of microtubule assembly in vitro by taxol

Peter B. Schiff, Jane Fant, Susan Band Horwitz · Nature · 1979 · 3.6K citations

, , +9

Structure of the αβ tubulin dimer by electron crystallography

Eva Nogales, Sharon G. Wolf, Kenneth H. Downing · Nature · 1998 · 2.1K citations

, , +13

Taxol stabilizes microtubules in mouse fibroblast cells.

Peter B. Schiff, S. B. Horwitz · Proceedings of the National Academy of Sciences · 1980 · 2K citations · Full text

, , +17

High-Resolution Model of the Microtubule

Eva Nogales, Michael Whittaker, Ronald A. Milligan et al. · Cell · 1999 · 1.2K citations · Full text

, , +12