From Bench to Humans: Formulation Development of a Poorly Water Soluble Drug to Mitigate Food Effect

A Theoretical Basis for a Biopharmaceutic Drug Classification: The Correlation of in Vitro Drug Product Dissolution and in Vivo Bioavailability

Gordon L. Amidon, Hans Lennernäs, Vinod P. Shah et al. · Pharmaceutical Research · 1995 · 5.3K citations · Full text

Pharmacy, Pharmacokinetics, Pharmacology +16

Evaluation of Various Dissolution Media for Predicting In Vivo Performance of Class I and II Drugs

Eric Galia, Eleftheria Nicolaides, D. Hörter et al. · Pharmaceutical Research · 1998 · 923 citations

Pharmacy, Pharmaceutics, Pharmacology +16

The role of biopharmaceutics in the development of a clinical nanoparticle formulation of MK-0869: a Beagle dog model predicts improved bioavailability and diminished food effect on absorption in human

Yunhui Wu, Alice E. Loper, Elizabeth Landis et al. · International Journal of Pharmaceutics · 2004 · 272 citations

Pharmacy, Pharmaceutics, Pharmacology +16

The Effects of Food on the Dissolution of Poorly Soluble Drugs in Human and in Model Small Intestinal Fluids

Eva Persson, Ann-Sofie Gustafsson, Anders S. Carlsson et al. · Pharmaceutical Research · 2005 · 264 citations

Pharmacy, Pharmaceutics, Pharmacology +14

Forecasting the In Vivo Performance of Four Low Solubility Drugs from Their In Vitro Dissolution Data

Eleftheria Nicolaides, Eric Galia, Constantin Efthymiopoulos et al. · Pharmaceutical Research · 1999 · 166 citations

Pharmacy, Pharmaceutics, Pharmacology +16