Napsamycins, new Pseudomonas active antibiotics of the mureidomycin family from Streptomyces sp. HIL Y-82, 11372.

Abstract

During the course of our screening program for antibiotics specifically active against Pseudomonas, we discovered four such new compounds which we named napsamycins A~D,1} from the culture filtrate ofa Streptomyces sp. HIL Y-82,1 1372 (DSM accession No. 5940). Chemical and spectroscopic analysis revealed that they belonged to the class of peptidylnucleoside antibiotics represented by the