Langmuir · 2008 · 20 citations · 22 references
Natural SciencesBioengineeringBiophysicsElectrophysiologyMembrane BiophysicsMembrane ScienceBiological MembranesLipid Bilayer StructureLipid BilayersMembrane CharacterizationMembrane EngineeringMembrane FabricationBlack Lipid MembranesElectrophysiological RecordingsFree-standing Lipid BilayersLipid Bilayer MembranesLong-term StabilityPlanar Lipid BilayersStructural Stability Of MembranesWet Etching
Silicon and Teflon substrates have been structured by wet etching and a focused ion beam (FIB) to obtain very defined, clean apertures. Planar, free-standing lipid membranes (black lipid membranes (BLM)) with enhanced long-term stability have been prepared on these apertures by the methods of Montal and Müller(1,2) as well as Müller and Rudin.(3) The stability and geometric control enables the use of X-ray analysis of free-standing single bilayers. With the presented setup, simultaneous structural and electrophysiological measurements will become feasible.
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Single-channel currents recorded from membrane of denervated frog muscle fibres
Erwin Neher, Bert Sakmann · Nature · 1976 · 2.5K citations
Phase-contrast imaging using polychromatic hard X-rays
S. Wilkins, Timur E. Gureyev, D. Gao et al. · Nature · 1996 · 1.8K citations