Chemical Communications · 2014 · 86 citations · 35 references
EngineeringBiochemistryChemistryAnalytical ChemistryBiosensorsEnzymologyBiological SensorsEnzymatic BiosensorsEnzyme DiagnosticsEnzyme-based BiosensorsFluorescence SpectroscopyMolecular Probe DevelopmentBiomedical ApplicationsBiomolecular DetectionChemical Biology ProbesFluorescence ProbesFluorescent BiosensingFluorescent Chemical ProbesFluorescent ProbesReal-time Monitoring
A highly selective long-wavelength fluorescent probe for the detection of human carboxylesterase 2 (hCE2) has been developed and well characterized. The probe can be used for measuring the real activities of hCE2 in complex biological systems.
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Clinical pharmacokinetics and metabolism of irinotecan (CPT-11).
Ron H.J. Mathijssen, R J van Alphen, Jaco J. Verweij et al. · PubMed · 2001 · 752 citations · Full text
Medicine, Oncology, Pharmacology +17
Characterization of CPT-11 hydrolysis by human liver carboxylesterase isoforms hCE-1 and hCE-2.
Rod Humerickhouse, K Lohrbach, Lin Li et al. · PubMed · 2000 · 356 citations
Man Tang, Madhu Mukundan, Jian Yang et al. · Journal of Pharmacology and Experimental Therapeutics · 2006 · 250 citations