Theopederins K and L. Highly Potent Cytotoxic Metabolites from a Marine Sponge <i>Discodermia</i> Species

Abstract

Theopederins K (1) and L (2) have been isolated from the marine sponge Discodermia sp. collected from Honduras. 1 and 2 showed in vitro cytotoxicity against P-388 and A-549 cell lines. The isolation, biological activities, and structure elucidation of theopederins K (1) and L (2) are described.