Highly Regioselective Functionalization of Aliphatic Carbon−Hydrogen Bonds with a Perbromohomoscorpionate Copper(I) Catalyst

Abstract

The complex Tp(Br3)Cu(NCMe) (1) is an excellent catalyst for the regioselective carbene transfer reaction to tertiary C-H bonds of hydrocarbons, at room temperature, using the readily available ethyl diazoacetate (EDA) as the carbene source.