A Tricyclic Polyamide Receptor for Carbohydrates in Organic Media

Abstract

The dissolution of glucose in chloroform is promoted by the receptor 1. Two biphenyl units and eight amide linkages line the cavity of 1, which was designed for complementarity to β-glucopyranosyl. Receptor 1 binds octyl glycosides with unusual affinities and stereoselectivities, even with methanol present as cosolvent.