Concepedia

4-N-linked-heterocyclic piperidine derivatives with high affinity and selectivity for human dopamine D4 receptors

Kevin W. Moore, Katrine Bonner, Elizabeth A. Jones, Frances Emms, Paul D. Leeson, R. Marwood, Shil Patel, Smita Patel, Michael Rowley, Steven R. Thomas,

Bioorganic & Medicinal Chemistry Letters · 1999 · 48 citations · 7 references

DOIFull text

Open access

Concepts

References

7

Dopamine D4 receptors elevated in schizophrenia

Philip Seeman, Hong‐Chang Guan, Hubert H.M. Van Tol · Nature · 1993 · 631 citations

, , +12

Are Striatal Dopamine D<sub>4</sub> Receptors Increased in Schizophrenia?

Gavin P. Reynolds, Sarah Mason · Journal of Neurochemistry · 1994 · 97 citations

, , +16

Elevation of D4 dopamine receptor mRNA in postmortem schizophrenic brain

Nicholas C. Stefanis, Janine Bresnick, Robert Kerwin et al. · Molecular Brain Research · 1998 · 69 citations

, , +12

1-(3-Cyanobenzylpiperidin-4-yl)-5-methyl-4-phenyl-1,3-dihydroimidazol-2-one:  A Selective High-Affinity Antagonist for the Human Dopamine D<sub>4</sub>Receptor with Excellent Selectivity over Ion Channels

Robert W. Carling, Kevin W. Moore, Christopher R. Moyes et al. · Journal of Medicinal Chemistry · 1999 · 53 citations · Full text

, , +17

Functional Coupling of Human D<sub>2</sub>, D<sub>3</sub>, and D<sub>4</sub> Dopamine Receptors in HEK293 Cells

George McAllister, Michael R. Knowles, S. M. Ward-Booth et al. · Journal of Receptors and Signal Transduction · 1995 · 43 citations

, , +17