Characterization of the bovine neurofilament NF-M protein and cDNA sequence, and identification of in vitro and in vivo calpain cleavage sites

CLUSTAL W: improving the sensitivity of progressive multiple sequence alignment through sequence weighting, position-specific gap penalties and weight matrix choice

Julie Thompson, Desmond G. Higgins, Toby J. Gibson · Nucleic Acids Research · 1994 · 64.9K citations · Full text

Life Sciences, Bioinformatics, Sequence Analysis +14

Amino Acid Sequences Common to Rapidly Degraded Proteins: The PEST Hypothesis

Scott W. Rogers, Rodney Wells, Martin Rechsteiner · Science · 1986 · 2.6K citations

Life Sciences, Biochemistry, Molecular Biology +16

PEST sequences and regulation by proteolysis

Martin Rechsteiner, Scott W. Rogers · Trends in Biochemical Sciences · 1996 · 1.6K citations

Life Sciences, Biochemistry, Molecular Biology +8

On the Sequential Determinants of Calpain Cleavage

Péter Tompa, Péter Buzder-Lantos, Ágnes Tantos et al. · Journal of Biological Chemistry · 2004 · 316 citations · Full text

Life Sciences, Biochemistry, Molecular Biology +17

Pattern-induced multi-sequence alignment (PUMA) algorithm employing secondary structure-dependent gap penalties for use in comparative protein modelling

Randall F. Smith, Temple F. Smmith · Protein Engineering Design and Selection · 1992 · 280 citations

Life Sciences, Bioinformatics, Biology +14