Localization of the Epileptogenic Zone by Ictal and Interictal SPECT with ^99mTc‐Ethyl Cysteinate Dimer in Patients with Medically Refractory Epilepsy

Abstract

These data demonstrate that ictal SPECT can be easily achieved by using 99mTc-ECD and can accurately localize the epileptogenic zone in both temporal and extratemporal epilepsies. Ictal ECD SPECT proved to be significantly more sensitive and specific than interictal ECD SPECT, and clinically useful in the definition of the epileptogenic zone.