Synthesis and binding affinities of a series of 1,2-benzisoxazole-3-carboxamides to dopamine and serotonin receptors

Relationship between the inhibition constant (KI) and the concentration of inhibitor which causes 50 per cent inhibition (I50) of an enzymatic reaction

Yung-Chi Cheng, William H. Prusoff · Biochemical Pharmacology · 1973 · 12.9K citations

Life Sciences, Biochemistry, Chemical Kinetics +14

Two-dimensional spectroscopy. Application to nuclear magnetic resonance

W.P Aue, E. Bartholdi, Richard R. Ernst · The Journal of Chemical Physics · 1976 · 3.1K citations

Natural Sciences, Physics, Nuclear Physics +13

Proton and carbon-13 assignments from sensitivity-enhanced detection of heteronuclear multiple-bond connectivity by 2D multiple quantum NMR

Ad Bax, Michael F. Summers · Journal of the American Chemical Society · 1986 · 2.5K citations

Natural Sciences, Chemistry, Nuclear Chemistry +7

Multiple Serotonin Receptors: Differential Binding of [3H]5-Hydroxytryptamine, [3H]Lysergic Acid Diethylamide and [3H]Spiroperidol

Stephen J. Peroutka, Solomon H. Snyder · Molecular Pharmacology · 1979 · 1.4K citations

Medicine, Neuroscience, Pharmacology +15

Sensitivity-enhanced two-dimensional heteronuclear shift correlation NMR spectroscopy

Ad Bax, Sankaran Subramanian · Journal of Magnetic Resonance (1969) · 1986 · 1.3K citations

Natural Sciences, Chemistry, Physics +6