Concepedia

Publication | Open Access

Elevated BCRP/ABCG2 Expression Confers Acquired Resistance to Gefitinib in Wild-Type EGFR-Expressing Cells

DOIFull Paper Access

78

Citations

39

References

2011

Year

Yun‐Ju Chen, Wei‐Chien Huang, Ya-Ling Wei, Sheng-Chieh Hsu, Ping Yuan, Heather Lin, Ignacio I. Wistuba, J. Jack Lee, Chia-Jui Yen, Wu‐Chou Su,
PLoS ONE

Abstract

Thus, BCRP/ABCG2 expression may be a predictor for poor efficacy of gefitinib treatment, and targeting BCRP/ABCG2 may broaden the use of gefitinib in patients with wtEGFR.

References

YearCitations

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