Phosphorylating agent for the synthesis of oligonucleotide with aliphatic amino group at 5′ end

DNA sequencing with chain-terminating inhibitors

Frederick Sanger, S. Nicklen, Alan Coulson · Proceedings of the National Academy of Sciences · 1977 · 69.3K citations · Full text

Life Sciences, Microbiology, Molecular Biology +10

[57] Sequencing end-labeled DNA with base-specific chemical cleavages

Allan M. Maxam, Walter Gilbert · Methods in enzymology on CD-ROM/Methods in enzymology · 1980 · 14.7K citations

Pharmacy, Biotechnology, Molecular Biology +13

Fluorescence detection in automated DNA sequence analysis

Lloyd M. Smith, Jane Z. Sanders, Robert Kaiser et al. · Nature · 1986 · 1.7K citations

Life Sciences, Biology, Molecular Biology +13

The synthesis of oligonucleotides containing an aliphatic amino group at the 5′ terminus: synthesis of fluorescent DNA primers for use in DNA sequence analysis

Lloyd M. Smith, Steven Fung, Michael W. Hunkapiller et al. · Nucleic Acids Research · 1985 · 337 citations · Full text

Pharmacy, Biochemistry, Molecular Biology +16

Efficient methods for attaching non-radioactive labels to the 5′ ends of synthetic oligodeoxyribonucleotides

Sudhir Agrawal, Chris Christodoulou, Michael J. Gait · Nucleic Acids Research · 1986 · 222 citations · Full text

Pharmacy, Biotechnology, Molecular Biology +17