Phosgene: A metabolite of chloroform

Relative effects of various chlorinated hydrocarbons on liver and kidney function in mice

Curtis D. Klaassen, Gàbriel L. Plaa · Toxicology and Applied Pharmacology · 1966 · 224 citations

Pharmacy, Environmental Sciences, Toxicology +16

Bioactivation of carbon tetrachloride, chloroform and bromotrichloromethane: Role of cytochrome P-450

I.G. Sipes, Gopal Krishna, James R. Gillette · Life Sciences · 1977 · 198 citations

Pharmacy, Chemistry, Toxicology +11

Chloroform toxicity in mice: Correlation of renal and hepatic necrosis with covalent binding of metabolites to tissue macromolecules

Kenneth F. Ilett, Watson D. Reid, I.G. Sipes et al. · Experimental and Molecular Pathology · 1973 · 177 citations

Veterinary Medicine, Biochemistry, Toxicology +16

METABOLISM OF CARBON TETRACHLORIDE AND CHLOROFORM BY THE RAT

Benoy B. Paul, David Rubinstein · Journal of Pharmacology and Experimental Therapeutics · 1963 · 135 citations

Life Sciences, Chemistry, Toxicology +9

Induction of Hepatomas in Mice by Repeated Oral Administration of Chloroform, with Observations on Sex Differences

Allen B. Eschenbrenner, Eliza C. Miller · JNCI Journal of the National Cancer Institute · 1945 · 121 citations

Medicine, Pathology, Toxicology +6