Integrated Analysis of Genome-Wide Methylation and Gene Expression Shows Epigenetic Regulation of <i>CYP11B2</i> in Aldosteronomas - Concepedia

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Integrated Analysis of Genome-Wide Methylation and Gene Expression Shows Epigenetic Regulation of <i>CYP11B2</i> in Aldosteronomas

DOI Full Paper Access

43

Citations

21

References

2013

Year

Brandi Howard, Yonghong Wang, Paraskevi Xekouki, Fábio R. Faucz, Meenu Jain, Lisa Zhang, Paul G. Meltzer, Constantine A. Stratakis, Electron Kebebew

The Journal of Clinical Endocrinology & Metabolism

Abstract

Altered methylation in aldosteronomas is associated with dysregulated expression of genes involved in steroid biosynthesis. Aldosteronomas are hypomethylated, and CYP11B2 is overexpressed and hypomethylated in these tumors.

References

	Year	Citations

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