Melanocortin-4 Receptors Expressed by Cholinergic Neurons Regulate Energy Balance and Glucose Homeostasis

Targeted Disruption of the Melanocortin-4 Receptor Results in Obesity in Mice

Dennis Huszar, Catherine Lynch, Victoria Fairchild-Huntress et al. · Cell · 1997 · 3K citations · Full text

Medicine, Endocrinology, Neuroscience +11

Role of melanocortinergic neurons in feeding and the agouti obesity syndrome

Wei Fan, Bruce A. Boston, Robert A. Kesterson et al. · Nature · 1997 · 1.9K citations

Life Sciences, Neurobiology, Neuroscience +14

Clinical Spectrum of Obesity and Mutations in the Melanocortin 4 Receptor Gene

I. Sadaf Farooqi, Julia M. Keogh, Giles S.H. Yeo et al. · New England Journal of Medicine · 2003 · 1.8K citations · Full text

Life Sciences, Endocrinology, Genetics +16

Divergence of Melanocortin Pathways in the Control of Food Intake and Energy Expenditure

Nina Balthasar, Louise T. Dalgaard, Charlotte E. Lee et al. · Cell · 2005 · 1.1K citations · Full text

Life Sciences, Neurobiology, Physiology +16

Localization of the melanocortin-4 receptor (MC4-R) in neuroendocrine and autonomic control circuits in the brain.

Kathleen G. Mountjoy, Marty Mortrud, Malcolm J. Low et al. · Molecular Endocrinology · 1994 · 1.1K citations · Full text

Life Sciences, Neurobiology, Neuroscience +17