Advanced Synthesis & Catalysis · 2005 · 517 citations · 89 references
Natural SciencesChemistryOrganic ChemistryHeterocycle SynthesisQuaternary StructureRetrosynthetic Analysis[4+2] CycloadditionAsymmetric C-c Bond FormationAsymmetric Heterocycle SynthesisCycloaddition ReactionsStereoselective Synthesis
Abstract Quaternary stereocenters are a particular challenge for stereoselective synthesis. With a central view on this specific structural issue, selected examples from the recent literature are highlighted in order to evaluate the state of the art of asymmetric CC bond formation. The review is divided into sections on addition and substitution reactions, rearrangements and cycloaddition reactions.
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