Polyethyleneimine-Based Core-Shell Nanogels: A Promising siRNA Carrier for Argininosuccinate Synthetase mRNA Knockdown in HeLa Cells

Replication-incompetent adenoviral vaccine vector elicits effective anti-immunodeficiency-virus immunity

John W. Shiver, Tong‐Ming Fu, Ling Chen et al. · Nature · 2002 · 1.2K citations · Full text

Life Sciences, Immunology, Infectious Diseases +10

RNAi-mediated gene-targeting through systemic application of polyethylenimine (PEI)-complexed siRNA in vivo

Beata Urban-Klein, Stephanie Werth, Shaker Abuharbeid et al. · Gene Therapy · 2004 · 707 citations

Pharmacy, Biotechnology, Molecular Biology +14

Physicochemical Parameters Associated with Nanoparticle Formation in the Salting-Out, Emulsification-Diffusion, and Nanoprecipitation Methods

Sergio Arturo Galindo-Rodríguez, Éric Allémann, Hatem Fessi et al. · Pharmaceutical Research · 2004 · 574 citations · Full text

Natural Sciences, Chemical Engineering, Chemistry +16

Simple Modifications of Branched PEI Lead to Highly Efficient siRNA Carriers with Low Toxicity

Arkadi Zintchenko, Alexander Philipp, Ali Dehshahri et al. · Bioconjugate Chemistry · 2008 · 466 citations · Full text

Pharmacy, Biotechnology, Molecular Biology +17

Pegylated arginine deiminase (ADI-SS PEG20,000 mw) inhibits human melanomas and hepatocellular carcinomas in vitro and in vivo.

Mark Ensor, Frederick W. Holtsberg, John S. Bomalaski et al. · PubMed · 2002 · 319 citations

Life Sciences, Biochemistry, Oncology +15