Direct calculation and computer simulation of the enantiomerization barrier of oxazepam in dynamic HPLC experiments—a comparative study

FDA'S policy statement for the development of new stereoisomeric drugs

Chirality · 1992 · 578 citations

Pharmacy, Medicinal Chemistry, Pharmaceutical Policy +11

The FDA perspective on the development of stereoisomers

Wilson H. De Camp · Chirality · 1989 · 286 citations

Pharmacy, Medicinal Chemistry, Pharmacology +12

Determination of enantiomerization barriers by dynamic and stopped‐flow chromatographic methods

Oliver Trapp, Gabriele Schoetz, Volker Schurig · Chirality · 2001 · 217 citations

Pharmacy, Medicinal Chemistry, Pharmaceutical Analysis +11

Determination of enantiomerization barriers by computer simulation of interconversion profiles: enantiomerization of diaziridines during chiral inclusion gas chromatography

Martin Jung, Volker Schurig · Journal of the American Chemical Society · 1992 · 176 citations

Pharmacy, Chemistry, Medicinal Chemistry +9

Stereointegrity of Tröger's Base:  Gas-Chromatographic Determination of the Enantiomerization Barrier

Oliver Trapp, Volker Schurig · Journal of the American Chemical Society · 2000 · 128 citations

Pharmacy, Chemistry, Analytical Chemistry +11