Concepedia

Total Synthesis of Polyoxygenated Cembrenes

Lutz F. Tietze, C. Christian Brazel, Sören Hölsken, Jörg Magull, A. Ringe

Angewandte Chemie International Edition · 2008 · 41 citations · 26 references

DOI

Concepts

Abstract

A convergent approach for the stereoselective construction of polyoxygenated cembrenes is reported. Key steps in the synthesis are an asymmetric domino multicomponent allylation, a modified Myers α-alkylation, and a ring-closing metathesis.

References

26

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Pseudoephedrine as a Practical Chiral Auxiliary for the Synthesis of Highly Enantiomerically Enriched Carboxylic Acids, Alcohols, Aldehydes, and Ketones

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