Total Synthesis of Polyoxygenated Cembrenes

Abstract

A convergent approach for the stereoselective construction of polyoxygenated cembrenes is reported. Key steps in the synthesis are an asymmetric domino multicomponent allylation, a modified Myers α-alkylation, and a ring-closing metathesis. Supporting information for this article is available on the WWW under http://www.wiley-vch.de/contents/jc_2002/2008/z800626_s.pdf or from the author. Please note: The publisher is not responsible for the content or functionality of any supporting information supplied by the authors. Any queries (other than missing content) should be directed to the corresponding author for the article.