An analytical framework in the general coalescent tree setting for analyzing polymorphisms created by two mutations

Gene Dose of Apolipoprotein E Type 4 Allele and the Risk of Alzheimer's Disease in Late Onset Families

Elizabeth H. Corder, Ann M. Saunders, Warren J. Strittmatter et al. · Science · 1993 · 9.5K citations

Life Sciences, Genetics, Neurology +17

Apolipoprotein E: high-avidity binding to beta-amyloid and increased frequency of type 4 allele in late-onset familial Alzheimer disease.

Warren J. Strittmatter, Ann M. Saunders, D. E. Schmechel et al. · Proceedings of the National Academy of Sciences · 1993 · 4.3K citations · Full text

Life Sciences, Genetics, Neurology +17

On the number of segregating sites in genetical models without recombination

G. A. Watterson · Theoretical Population Biology · 1975 · 4.1K citations

Life Sciences, Biology, Genetics +8

EVOLUTIONARY RELATIONSHIP OF DNA SEQUENCES IN FINITE POPULATIONS

Fumio Tajima · Genetics · 1983 · 3.2K citations · Full text

Life Sciences, Evolutionary Biology, Genetics +17

Mitochondrial DNA and human evolution

Rebecca L. Cann, Mark Stoneking, Allan C. Wilson · Nature · 1987 · 3.1K citations

Medicine, Evolutionary Biology, Genetics +14