Concepedia

Publication | Open Access

Telomere shortening and inactivation of cell cycle checkpoints characterize human hepatocarcinogenesis†

DOIFull Paper Access

144

Citations

38

References

2007

Year

Ruben R. Plentz, Young Nyun Park, André Lechel, Haeryoung Kim, Friederike Nellessen, Britta Heike Eva Langkopf, Ludwig Wilkens, Annarita Destro, Barbara Fiamengo, Michael P. Manns,
Hepatology

Abstract

The inactivation of cell cycle checkpoints coincides with further telomere shortening and an accumulation of DNA damage in SCC and HCC, suggesting that SCC represent more advanced precursor lesions compared with LCC.

References

YearCitations

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