Investigative Radiology · 1990 · 361 citations · 0 references
MedicineRadiologyDiagnostic ImagingDiagnostic RadiologyImage InterpretationBreast AssessmentBreast ImagingCancer DetectionComputer-aided DiagnosisMedical Image AnalysisMedical ImagingComputer-aided DetectionDiagnostic Accuracy StudiesFalse Positive Rate AnalysisFalse Positive Rate EvaluationFalse Positive Rate ReductionMammography False PositivesReceiver Operating Characteristic AnalysisScreening Mammography
Relatively simple, but important, detection tasks in radiology are nearing accessibility to computer-aided diagnostic (CAD) methods. The authors have studied one such task, the detection of clustered microcalcifications on mammograms, to determine whether CAD can improve radiologists' performance under controlled but generally realistic circumstances. The results of their receiver operating characteristic (ROC) study show that CAD, as implemented by their computer code in its present state of development, does significantly improve radiologists' accuracy in detecting clustered microcalcifications under conditions that simulate the rapid interpretation of screening mammograms. The results suggest also that a reduction in the computer's false-positive rate will further improve radiologists' diagnostic accuracy, although the improvement falls short of statistical significance in this study.