Immunohistochemical detection of <i><scp>H</scp>elicobacter pylori</i> without association of <scp>TLR</scp>5 expression in oral squamous cell carcinoma

Abstract

For the first time, this study provides evidence that immunohistochemically detected HP expression in OSCC is associated with reduced disease-free survival in a large patient cohort. Although TLR5 was not associated with any clinicopathological characteristics or impact on survival, investigation of the TLR family seems to be reasonable due to the possible existence of other pathogenic bacterial or viral compounds in oral cavity cancer.