Rabbit 19 <i>S</i> Antibodies with Allotypic Specificities of the <i>a</i> -Locus Group

Abstract

Activity of bacteriophage T4 neutralizing antiserums obtained 8 days after a primary immunization of rabbits with purified phage T4 is due to antibodies of the 19S (IgM) type. This neutralizing activity could be partially inhibited by treatment with excess antiserum directed against the a-locus group allotypic specificity carried by the whole rabbit serum.