Synthesis and antiinflammatory and analgesic activity of amidines of 3,4-dihydroisoquinoline series

Carrageenin-Induced Edema in Hind Paw of the Rat as an Assay for Antiinflammatory Drugs

C. A. Winter, Edwin A. Risley, George W. Nuss · Experimental Biology and Medicine · 1962 · 5.6K citations

Inflammation, Rheumatology, Anti-inflammatory +13

ACETIC ACID FOR ANALGESIC SCREENING

R Koster, W. N. Anderson, Edwin J. de Beer · Medical Entomology and Zoology · 1959 · 2.1K citations

Medicinal Chemistry, Health Sciences, Pain Medicine +7

1-Aminoisoquinoline as benzamidine isoster in the design and synthesis of orally active thrombin inhibitors

J. B. M. Rewinkel, Hans Lucas, Philip J. M. van Galen et al. · Bioorganic & Medicinal Chemistry Letters · 1999 · 54 citations · Full text

Combinatorial Chemistry, Benzamidine Isoster, Medicinal Chemistry +10

Molecular modeling of 3-arylisoquinoline antitumor agents active against A-549. A comparative molecular field analysis study

Won-Jea Cho, Eui-Ki Kim, Il Yeong Park et al. · Bioorganic & Medicinal Chemistry · 2002 · 44 citations

Medicinal Chemistry, Drug Target, Biochemistry +11

Synthesis and antihypertensive activity of 1-amino-3,4-dihydroisoquinolines

Guy D. Diana, William B. Hinshaw, Harlan E. Lape · Journal of Medicinal Chemistry · 1977 · 16 citations

Pharmaceutical Science, Bioorganic Chemistry, Altmetric Attention Score +18